Article
Association of the CAT-262C>T polymorphism with asthma in smokers and the nonemphysematous phenotype of chronic obstructive pulmonary disease.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Jul 2014
Taniguchi Natsuko, Konno Satoshi, Isada Akira, Hattori Takeshi, Kimura Hirokazu, Shimizu Kaoruko, Maeda Yukiko, Makita Hironi, Hizawa Nobuyuki, Nishimura Masaharu
Abstract excerpt
BACKGROUND: Catalase (CAT) is a part of the active antioxidant defense system and has been studied with regard to its association with asthma and chronic obstructive pulmonary disease (COPD), which are heterogeneous obstructive pulmonary diseases characterized by chronic airway inflammation. We hypothesized that the CAT gene might be involved in the common pathogenesis underlying asthma and COPD. OBJECTIVE: To...
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