Article
Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2009
Hodges Laura M, Weissman Myrna M, Haghighi Fatemeh, Costa Ramiro, Bravo Oscar, Evgrafov Oleg, Knowles James A, Fyer Abby J, Hamilton Steven P
Abstract excerpt
Panic disorder (PD) is a debilitating anxiety disorder, characterized by recurrent episodes of intense fear that are accompanied by autonomic and psychological symptoms leading to behavioral impairment. Basic research implicates neuropeptide-signaling genes in the modulation of anxiety and stress. The genes encoding corticotropin releasing hormone receptor 1 (CRHR1), tachykinin receptor 1 (TACR1), gastrin...
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