Article
A DNA polymorphism of stromal-derived factor-1 is associated with advanced stages of oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Vylliotis Antonis, Spyridonodou Sofia, Derka Spyridoula, Vassiliou Stavros, Nkenke Emeka, Yapijakis Christos, Serefoglou Zoe, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
BACKGROUND: Stromal derived factor-1 (SDF-1), a protein related to angiogenesis and inflammation, has been correlated with the progression of a number of malignancies, but not with oral squamous cell carcinoma. In light of the known contribution to the development of oral cancer of other gene polymorphisms for proteins responsible for angiogenesis, inflammation and thrombosis, this study investigated whether the...
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