Article
Single nucleotide polymorphisms of the vascular endothelial growth factor gene associated with incidence of oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2010
Kämmerer Peer W, Toyoshima Takeshi, Eletr Sami, Kämmerer Philipp, Kuhr Kathrin, Al-Nawas Bilal, Brieger Jürgen
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor (VEGF) plays an important role in promoting angiogenesis and is overexpressed in several malignancies. Polymorphisms of the VEGF gene can alter VEGF protein expression, which may be biologically significant and account for heterogeneity in disease risk and outcome. The aim of this case-control study was to evaluate potential associations between single nucleotide...
Topics
- Aged
- Carcinoma, Squamous Cell
- Case-Control Studies
- Humans
- Male
- Matched-Pair Analysis
- Middle Aged
- Mouth Neoplasms
- Polymorphism, Single Nucleotide