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Article

Polymorphisms in the hypoxia inducible factor 1-alpha and the impact on the prognosis of early stages of oral cancer.

Annals of surgical oncology - 1 Aug 2009

Muñoz-Guerra Mario Fernando, Fernández-Contreras María Encarnación, Moreno Ana Laura Capote, Martín Irene Domínguez, Herráez Belén, Gamallo Carlos

Abstract excerpt

BACKGROUND: Hypoxia-inducible factor-1 (HIF-1) is the key regulator of cellular responses to hypoxia and presumably plays a central role in the control of tumor growth. Polymorphisms or mutations increasing its activity and stability in vitro under normoxia have recently been identified. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19449077
DOI: 10.1245/s10434-009-0503-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19449077-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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