Article
Modulation of astrocytic metabolic phenotype by proinflammatory cytokines.
Glia - 1 Jul 2008
Gavillet Mathilde, Allaman Igor, Magistretti Pierre J
Abstract excerpt
Astrocytes play an important role in nervous system homeostasis. In particular, they contribute to the regulation of local energy metabolism and to oxidative stress defence. In previous experiments, we showed that long-term treatment with interleukin 1alpha (IL-1alpha) or tumor necrosis factor-alpha (TNFalpha) alone increases glucose utilization in primary culture of mouse astrocytes. In our study, we report that...
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