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Article

Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype.

Neurotoxicity research - 1 Jan 2005

Zagami Chrissandra J, O'Shea Ross D, Lau Chew L, Cheema Surindar S, Beart Philip M

Abstract excerpt

The astrocytic glutamate transporters, EAAT1 and EAAT2, remove released L-glutamate from the synaptic milieu thereby maintaining normal excitatory transmission. EAAT dysfunction during the excitotoxicity and oxidative stress of neurological insults may involve homoeostatic mechanisms associated with astrocytic function. We investigated aspects of EAAT function and expression in concert with astrocytic phenotype...

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Source

Identifiers

PMID: 15639805
DOI: 10.1007/BF03033783

Genes

GFAP
MAP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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