Article
A family-based likelihood ratio test for general pedigree structures that allows for genotyping error and missing data.
Human heredity - 1 Jan 2008
Yang Yang, Wise Carol A, Gordon Derek, Finch Stephen J
Abstract excerpt
The purpose of this work is the development of a family-based association test that allows for random genotyping errors and missing data and makes use of information on affected and unaffected pedigree members. We derive the conditional likelihood functions of the general nuclear family for the following scenarios: complete parental genotype data and no genotyping errors; only one genotyped parent and no...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.