Article

Differential Analysis of Stromal-Epithelial Interactions between In Situ and Invasive Breast Cancer using Gene Expression Profiling

2022-08-02

Abstract excerpt

<h4>Background</h4> Changes in microenvironment cell-cell interactions (CCI) during the progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) are poorly understood. Gene expression studies are confounded by cellular heterogeneity and few separate stromal and epithelial contributions, resulting in a lack of reliable prognostic biomarker to guide treatment decisions. <h4>Methods</h4>...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5d3d7c2-531c-5fa1-8ce3-6de243ceaa73
DOI: 10.1101/2022.07.30.502150

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Differential Analysis of Stromal-Epithelial Interactions between In Situ and Invasive Breast Cancer using Gene Expression ProfilingDOI 10.1101/2022.07.30.502150Read

Cell non-autonomous interactions during non-immune stromal progression in the breast tumor microenvironmentSemantic proximity Read

Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma <i>In Situ</i> to Invasive Breast CancerSemantic proximity Read

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breastSemantic proximity Read

Cellular stemness identifies high-risk ductal carcinoma <i>in situ</i> and offers a therapeutic interception opportunitySemantic proximity Read

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.Semantic proximity Read

Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In SituSemantic proximity Read

Tumor microenvironmental determinants of high-risk DCIS progressionSemantic proximity Read

A Molecular Portrait of High-Grade Ductal Carcinoma In Situ.Semantic proximity Read

Tumor microenvironmental determinants of high-risk DCIS progressionSemantic proximity Read

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohortsSemantic proximity Read

Intercellular Molecular Crosstalk Networks within Invasive and Immunosuppressive Tumor Microenvironment Subtypes Associated with Clinical Outcomes in Four Cancer TypesSemantic proximity Read

Gene Expression Patterns Associated with Tumor-Infiltrating CD4+ and CD8+ T Cells in Invasive Breast CarcinomasSemantic proximity Read