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Article

Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume.

The British journal of psychiatry : the journal of mental science - 1 Apr 2008

Young Keith A, Bonkale Willy L, Holcomb Leigh A, Hicks Paul B, German Dwight C

Abstract excerpt

BACKGROUND: The 5HTTLPR genetic variant of the serotonin transporter gene (SERT or 5-HTT), which is comprised of a short (SERT-s) and a long (SERT-l) allele, is associated with major depressive disorder and post-traumatic brain disorder. AIMS: The present study sought to determine whether the total thalamus and major subregions are altered in size in major depressive disorder and in relation to the 5HTTLPR...

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Share to Antidepressive Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Share to Serotonin Plasma Membrane Transport Proteins

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Source

Identifiers

PMID: 18378990
DOI: 10.1192/bjp.bp.107.039180

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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