The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.

doi:10.1177/0269881117732514

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.

Journal of psychopharmacology (Oxford, England) - 1 Dec 2017

Niciu Mark J, Iadarola Nicolas D, Banerjee Dipavo, Luckenbaugh David A, Park Minkyung, Lener Marc, Park Lawrence, Ionescu Dawn F, Ballard Elizabeth D, Brutsche Nancy E, Akula Nirmala, McMahon Francis J, Machado-Vieira Rodrigo, Nugent Allison C, Zarate Carlos A

Abstract excerpt

BACKGROUND: This study sought to reproduce, in a larger sample, previous findings of a correlation between smaller raw 3-Tesla (3T) hippocampal volumes and improved antidepressant efficacy of ketamine in individuals with major depressive disorder (MDD). A secondary analysis stratified subjects according to functional BDNF rs6265 (val66met) genotype. METHODS: Unmedicated subjects with treatment-resistant MDD (...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amygdala

Share to Antidepressive Agents

Share to Atrophy

Share to Brain-Derived Neurotrophic Factor

Share to Depressive Disorder, Major

Share to Double-Blind Method

Share to Neuroimaging

Share to Thalamus

Source

Open in PubMed Open full text

Identifiers

PMID: 29039254
DOI: 10.1177/0269881117732514
PMCID: PMC5863225

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.PMID 29039254Read ↗

Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression.Semantic proximity Read ↗

Imaging phenotypes of major depressive disorder: genetic correlates.Semantic proximity Read ↗

Impact of monoamine-related gene polymorphisms on hippocampal volume in treatment-resistant depression.Semantic proximity Read ↗

Hippocampal volume and serotonin transporter polymorphism in major depressive disorderSemantic proximity Read ↗

The BDNF Val66Met polymorphism impacts parahippocampal and amygdala volume in healthy humans: incremental support for a genetic risk factor for depression.Semantic proximity Read ↗

No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression.Semantic proximity Read ↗

BDNF Val66Met polymorphism and hippocampal volume in neuropsychiatric disorders: A systematic review and meta-analysis.Semantic proximity Read ↗

Blood biomarker changes in response to low-dose oral ketamine treatment in adults with major depressive disorder (MDD) and post-traumatic stress disorder (PTSD)Semantic proximity Read ↗

Alterations in subcortical magnetic susceptibility and disease-specific relationship with brain volume in major depressive disorder and schizophreniaSemantic proximity Read ↗

Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder.Semantic proximity Read ↗

Influence of BDNF rs10835210 on right parahippocampal volume and its related cognitive function in first- and multiple-episode bipolar disorder.Semantic proximity Read ↗

The importance of identifying functional Val158Met polymorphism in catechol-O- Methyltransferase when assessing MRI-based volumetric measurements in major depressive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.