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Article

Reduced Candida glabrata susceptibility secondary to an FKS1 mutation developed during candidemia treatment.

Antimicrobial agents and chemotherapy - 1 Jun 2008

Cleary John D, Garcia-Effron Guillermo, Chapman Stanley W, Perlin David S

Abstract excerpt

We describe a case of recurring Candida glabrata infection in a 68-year-old African-American female on caspofungin therapy. The initial isolate was susceptible, but isolates recovered during following relapses were not. All isolates were clonal, and high-MIC strains contained a mutation in the highly conserved hot spot 1 region of Fks1p.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18378714
DOI: 10.1128/AAC.01568-07
PMCID: PMC2415792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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