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Article

Mitochondrial DNA somatic mutations are frequent in nasopharyngeal carcinoma.

Cancer biology & therapy - 1 Feb 2008

Pang Ling-Juan, Shao Jian-Yong, Liang Xiao-Man, Xia Yun-Fei, Zeng Yi-Xin

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China, and is highly sensitive to radiotherapy. The control region (D-loop) of mtDNA is a polymorphic region in which point mutations occur frequently. In this study, point mutation and common deletion (CD) mutations were investigated in 23 samples of NPC tumor tissue and in the radiation-treated NPC cell line CNE2. Polymorphisms at 72...

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Identifiers

PMID: 18376149
DOI: 10.4161/cbt.7.2.5256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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