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Article

Multiplexed assays for detection of mutations in PIK3CA.

Clinical chemistry - 1 Apr 2008

Board Ruth E, Thelwell Nicola J, Ravetto Paul F, Little Stephen, Ranson Malcolm, Dive Caroline, Hughes Andrew, Whitcombe David

Abstract excerpt

BACKGROUND: Mutations in the PIK3CA gene (phosphoinositide-3-kinase, catalytic, alpha polypeptide) have recently been described in a number of cancers, and their detection is currently limited because of the low sensitivity of conventional sequencing techniques. METHODS: We combined Amplification...

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Identifiers

PMID: 18375489
DOI: 10.1373/clinchem.2007.098376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18375489-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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