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Article

DNA repair in murine embryonic stem cells and differentiated cells.

Experimental cell research - 10 Jun 2008

Tichy Elisia D, Stambrook Peter J

Abstract excerpt

Embryonic stem (ES) cells are rapidly proliferating, self-renewing cells that have the capacity to differentiate into all three germ layers to form the embryo proper. Since these cells are critical for embryo formation, they must have robust prophylactic mechanisms to ensure that their genomic integrity is preserved. Indeed, several studies have suggested that ES cells are hypersensitive to DNA damaging agents...

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Identifiers

PMID: 18374918
DOI: 10.1016/j.yexcr.2008.02.007
PMCID: PMC2532524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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