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Article

Role of response gene to complement 32 in diseases

29 Mar 2008

Abstract excerpt

The role of response gene to complement (RGC)-32 as a cell cycle regulator has been attributed to its ability to activate cdc2 kinases and to induce S-phase entry and mitosis. However, recent studies revealed novel functions for RGC-32 in diverse processes such as cellular differentiation, inflammation, and fibrosis. Besides responding to C5b-9 stimulation, RGC-32 expression is also induced by growth factors,...

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PMID: 18373239
DOI: 10.1007/s00005-008-0016-3

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