Article
Knockdown of response gene to complement 32 (RGC32) induces apoptosis and inhibits cell growth, migration, and invasion in human lung cancer cells.
Molecular and cellular biochemistry - 1 Sept 2014
Xu Ran, Shang Chao, Zhao Jungang, Han Yun, Liu Jun, Chen Kuanbing, Shi Wenjun
Abstract excerpt
Response gene to complement 32 (RGC32) is a novel protein originally identified as a cell cycle activator and has been demonstrated to be overexpressed in a variety of human malignancies, including lung cancer. However, the potential role of RGC32 in lung cancer initiation and progression remains to be elucidated. In the present study, RNA interference mediated by plasmid expressing RGC32 short-hairpin RNA...
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