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Article

Regulator of Cell Cycle Protein (RGCC/RGC-32) Protects Against Pulmonary Fibrosis

20 Oct 2021

Abstract excerpt

Abstract Some previous studies in tissue fibrosis have suggested a profibrotic contribution from elevated expression of a protein termed either RGCC (regulator of cell cycle) or RGC-32 (response gene to complement 32 protein). Our analysis of public gene expression datasets, by contrast, revealed a consistent decrease in RGCC mRNA levels in association with pulmonary fibrosis. Consistent with this observation, we...

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PMID: 34668840
DOI: 10.1165/rcmb.2021-0022oc

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