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Article

Role of C5b-9 and RGC-32 in Cancer

9 May 2019

Abstract excerpt

The complement system represents an effective arsenal of innate immunity as well as an interface between innate and adaptive immunity. Activation of the complement system culminates with the assembly of the C5b-9 terminal complement complex on cell membranes, inducing target cell lysis. Translation of this sequence of events into a malignant setting has traditionally afforded C5b-9 a strict antitumoral role, in...

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PMID: 31156630
DOI: 10.3389/fimmu.2019.01054

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