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Article

Complement System: Promoter or Suppressor of Cancer Progression?

25 Oct 2020

Abstract excerpt

Constituent of innate immunity, complement is present in the tumor microenvironment. The functions of complement include clearance of pathogens and maintenance of homeostasis, and as such could contribute to an anti-tumoral role in the context of certain cancers. However, multiple lines of evidence show that in many cancers, complement has pro-tumoral actions. The large number of complement molecules (over 30),...

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PMID: 33113844
DOI: 10.3390/antib9040057

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