Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the GAA1013-->GAG polymorphism of the insulin-like growth factor-1 receptor (IGF1R) gene with premature pubarche.

Fertility and sterility - 1 Aug 2007

Roldan Maria Belen, White Carlie, Witchel Selma Feldman

Abstract excerpt

OBJECTIVE: A single-nucleotide polymorphism (SNP), the G variant in codon 1013 (GAA1013-->GAG) of the insulin-like growth factor-1 (IGF-1) receptor (IGFIR) gene, has been associated with higher IGF-1 concentrations in Caucasian subjects. Because elevated serum levels of IGF-1 have been described in children with premature pubarche (PP) and in adolescent girls with hyperandrogenism, we tested the a priori...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Child, Preschool
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin Resistance

Share to Longitudinal Studies

Share to Puberty, Precocious

Share to Receptor, IGF Type 1

Share to Steroid 21-Hydroxylase

Source

Identifiers

PMID: 17442315
DOI: 10.1016/j.fertnstert.2006.11.126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the GAA1013-->GAG polymorphism of the insulin-like growth factor-1 receptor (IGF1R) gene with premature pubarche.PMID 17442315Read ↗

Candidate gene analysis in premature pubarche and adolescent hyperandrogenism.Semantic proximity Read ↗

Increased frequency of the G972R variant of the insulin receptor substrate-1 (irs-1) gene among girls with a history of precocious pubarche.Semantic proximity Read ↗

Association of the -243 A-->G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche.Semantic proximity Read ↗

Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians.Semantic proximity Read ↗

Frequency of the T228A polymorphism in the SORBS1 gene in children with premature pubarche and in adolescent girls with hyperandrogenism.Semantic proximity Read ↗

Vitamin D receptor gene polymorphisms and sex steroid secretion in girls with precocious pubarche in Southern Brazil: a pilot study.Semantic proximity Read ↗

Insulin resistance after precocious pubarche: relation to PAI-1-675 4G/5G polymorphism, and opposing influences of prenatal and postnatal weight gain.Semantic proximity Read ↗

Insulin gene variable number of tandem repeat genotype and the low birth weight, precocious pubarche, and hyperinsulinism sequence.Semantic proximity Read ↗

Molecular defects of the CYP21 gene in Spanish girls with isolated precocious pubarche.Semantic proximity Read ↗

No association between body mass index and beta(3)-adrenergic receptor variant (W64R) in children with premature pubarche and adolescent girls with hyperandrogenism.Semantic proximity Read ↗

Inter- and intrafamilial variability in premature pubarche and polycystic ovary syndrome.Semantic proximity Read ↗

Insulin gene polymorphism and premature male pattern baldness in the general population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.