Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

'Insulator bodies' are aggregates of proteins but not of insulators.

EMBO reports - 1 May 2008

Golovnin Anton, Melnikova Larisa, Volkov Ilya, Kostuchenko Margarita, Galkin Alexander V, Georgiev Pavel

Abstract excerpt

Chromatin insulators are thought to restrict the action of enhancers and silencers. The best-known insulators in Drosophila require proteins such as Suppressor of Hairy wing (Su(Hw)) and Modifier of mdg4 (Mod(mdg4)) to be functional. The insulator-related proteins apparently colocalize as nuclear speckles in immunostained cells. It has been asserted that these speckles are 'insulator bodies' of many...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Recombinant Proteins

Share to Repressor Proteins

Share to Transgenes

Share to Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 18369369
DOI: 10.1038/embor.2008.32
PMCID: PMC2373365

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

'Insulator bodies' are aggregates of proteins but not of insulators.PMID 18369369Read ↗

The gypsy insulator of Drosophila affects chromatin structure in a directional manner.Semantic proximity Read ↗

Polycomb and trithorax group proteins mediate the function of a chromatin insulator.Semantic proximity Read ↗

Investigation of the properties of non-gypsy suppressor of hairy-wing-binding sites.Semantic proximity Read ↗

Faint gray bands in Drosophila melanogaster polytene chromosomes are formed by coding sequences of housekeeping genes.Semantic proximity Read ↗

Drosophila histone locus bodies form by hierarchical recruitment of components.Semantic proximity Read ↗

EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster.Semantic proximity Read ↗

Insulators are fundamental components of the eukaryotic genomes.Semantic proximity Read ↗

Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance.Semantic proximity Read ↗

Characterization of functional domains of the su(Hw) protein that mediate the silencing effect of mod(mdg4) mutations.Semantic proximity Read ↗

Trans-splicing of the mod(mdg4) complex locus is conserved between the distantly related species Drosophila melanogaster and D. virilis.Semantic proximity Read ↗

Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex.Semantic proximity Read ↗

Multiple interactions are involved in a highly specific association of the Mod(mdg4)-67.2 isoform with the Su(Hw) sites in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.