Article
Copy number variant analysis of human embryonic stem cells.
Stem cells (Dayton, Ohio) - 1 Jun 2008
Wu Hao, Kim Kevin J, Mehta Kshama, Paxia Salvatore, Sundstrom Andrew, Anantharaman Thomas, Kuraishy Ali I, Doan Tri, Ghosh Jayati, Pyle April D, Clark Amander, Lowry William, Fan Guoping, Baxter Tim, Mishra Bud, Sun Yi, Teitell Michael A
Abstract excerpt
Differences between individual DNA sequences provide the basis for human genetic variability. Forms of genetic variation include single-nucleotide polymorphisms, insertions/duplications, deletions, and inversions/translocations. The genome of human embryonic stem cells (hESCs) has been characterized mainly by karyotyping and comparative genomic hybridization (CGH), techniques whose relatively low resolution at...
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