Article
Protein kinase A phosphorylation of spinophilin modulates its interaction with the alpha 2A-adrenergic receptor (AR) and alters temporal properties of alpha 2AAR internalization.
The Journal of biological chemistry - 23 May 2008
Xu Jianmin, Chen Yunjia, Lu Roujian, Cottingham Christopher, Jiao Kai, Wang Qin
Abstract excerpt
Spinophilin plays critical roles in regulating trafficking and signaling of the alpha(2)-adrenergic receptor (AR) both in vitro and in vivo (Wang, Q., Zhao, J., Brady, A. E., Feng, J., Allen, P. B., Lefkowitz, R. J., Greengard, P., and Limbird, L. E. (2004) Science 304, 1940-1944). In the present...
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