Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

XRCC1 codon 399 mutant allele: a risk factor for recurrence of urothelial bladder carcinoma in patients on BCG immunotherapy.

Cancer biology & therapy - 1 May 2008

Mittal Rama Devi, Singh Ranjana, Manchanda Parmeet Kaur, Ahirwar Dinesh, Gangwar Ruchika, Kesarwani Pravin, Mandhani Anil

Abstract excerpt

XRCC1 protein plays crucial role in base excision repair (BER)by acting as a scaffold for other BER enzymes. Variants in XRCC1 gene might alter protein structure/function or create alternatively spliced protein influencing BER efficiency and affect individual susceptibility/recurrence to urinary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Urinary Bladder Neoplasms
Share to BCG Vaccine
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Immunotherapy

Share to Urothelium

Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 18364571
DOI: 10.4161/cbt.7.5.5763

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18364571-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

XRCC1 codon 399 mutant allele: a risk factor for recurrence of urothelial bladder carcinoma in patients on BCG immunotherapy.PMID 18364571Read ↗

Impact of nucleotide excision repair ERCC2 and base excision repair APEX1 genes polymorphism and its association with recurrence after adjuvant BCG immunotherapy in bladder cancer patients of North India.Semantic proximity Read ↗

XRCC1 Arg194Trp and Arg280His polymorphisms in bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

DNA repair gene XRCC1 polymorphisms, smoking, and bladder cancer risk: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to glioma.Semantic proximity Read ↗

XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asian population: evidence from a meta-analysis.Semantic proximity Read ↗

Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case-control study.Semantic proximity Read ↗

XPC gene variants: a risk factor for recurrence of urothelial bladder carcinoma in patients on BCG immunotherapy.Semantic proximity Read ↗

The codon 399 Arg/Gln XRCC1 polymorphism is associated with lung cancer in Indians.Semantic proximity Read ↗

A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder cancer risk.Semantic proximity Read ↗

Gene variants of XRCC4 and XRCC3 and their association with risk for urothelial bladder cancer.Semantic proximity Read ↗

DNA repair gene XRCC1 polymorphisms and bladder cancer risk.Semantic proximity Read ↗

Single-nucleotide polymorphisms in BER and HRR genes, XRCC1 haplotypes and breast cancer risk in Caucasian women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.