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Article

Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to glioma.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Hu Xue-Bin, Feng Zhe, Fan Yu-Cong, Xiong Zhi-Yong, Huang Qi-Wei

Abstract excerpt

BACKGROUND: The XRCC1 gene encodes the XRCC1 protein, which complexes with three other DNA repair enzymes involved in the base-excision repair (BER) pathways. Different XRCC1 polymorphisms may increase the risk of cancers by impairing interaction with other enzymatic proteins and consequently altering DNA repair activity, and result in carcinogenesis. Our study aimed to investigate any association between three...

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PMID: 22393975

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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