Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.

Human molecular genetics - 1 Jul 2008

Capon Francesca, Bijlmakers Marie-José, Wolf Natalie, Quaranta Maria, Huffmeier Ulrike, Allen Michael, Timms Kirsten, Abkevich Victor, Gutin Alexander, Smith Rhodri, Warren Richard B, Young Helen S, Worthington Jane, Burden A David, Griffiths Christopher E M, Hayday Adrian, Nestle Frank O, Reis Andre, Lanchbury Jerry, Barker Jonathan N, Trembath Richard C

Abstract excerpt

Psoriasis is an immune-mediated skin disorder that is inherited as a multifactorial trait. Linkage studies have clearly identified a primary disease susceptibility locus lying within the major histocompatibility complex (MHC), but have generated conflicting results for other genomic regions. To overcome this difficulty, we have carried out a genome-wide association scan, where we analyzed more than 408,000 SNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Genome, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Proteins

Share to Psoriasis

Share to Recombinant Fusion Proteins

Share to Ubiquitin

Share to Ubiquitin-Protein Ligases

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 18364390
DOI: 10.1093/hmg/ddn091
PMCID: PMC2900900

Genes

SPATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.PMID 18364390Read ↗

Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.Semantic proximity Read ↗

Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.Semantic proximity Read ↗

Genome-wide association analysis identifies three psoriasis susceptibility loci.Semantic proximity Read ↗

Unraveling the genetics of complex diseases: susceptibility genes for rheumatoid arthritis and psoriasis.Semantic proximity Read ↗

Sequencing-based approach identified three new susceptibility loci for psoriasis.Semantic proximity Read ↗

Computational Identification of RNF114 nsSNPs with Potential Roles in Psoriasis and Immune Dysregulation.Semantic proximity Read ↗

Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that is distinct from other autoimmune diseases.Semantic proximity Read ↗

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.Semantic proximity Read ↗

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis.Semantic proximity Read ↗

Fine mapping of eight psoriasis susceptibility loci.Semantic proximity Read ↗

Different epigenome regulation and transcriptome expression of CD4+ and CD8+ T cells from monozygotic twins discordant for psoriasisSemantic proximity Read ↗

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.