Article
Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.
Archives of dermatological research - 1 Apr 2014
Dębniak T, Soczawa E, Boer M, Różewicka-Czabańska M, Wiśniewska J, Serrano-Fernandez P, Mirecka A, Paszkowska-Szczur K, Lubinski J, Krysztoforska L, Adamski Z, Maleszka R
Abstract excerpt
Psoriasis vulgaris is a genetically heterogenous disease with unclear molecular background. We assessed the association of psoriasis and its main clinical phenotypes with common variants of three potential psoriasis susceptibility genes: ZNF750, RPTOR and TRAF31P2. We genotyped 10 common variants in a cohort of 1,034 case-control individuals using Taqman genotyping assays and sequencing. Minor alleles of all four...
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