Article
Rapid selection response for contextual fear conditioning in a cross between C57BL/6J and A/J: behavioral, QTL and gene expression analysis.
Behavior genetics - 1 May 2008
Ponder Christine A, Huded Chetan P, Munoz Michaelanne B, Gulden Forrest O, Gilliam T Conrad, Palmer Abraham A
Abstract excerpt
We used short-term selection to produce outbred mouse lines with differences in contextual fear conditioning. Within two generations of selection all low selected mice were homozygous for the recessive tyrc allele and showed the corresponding albino coat color. Freezing differed in the high and low selected lines across a range of parameters. We identified several QTLs for the selection response, including a...
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