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Article

Brain region-specific expression of genes mapped within quantitative trait loci for behavioral responsiveness to acute stress in Fisher 344 and Wistar Kyoto male rats.

PloS one - 1 Jan 2018

Meckes Jeanie K, Lim Patrick H, Wert Stephanie L, Luo Wendy, Gacek Stephanie A, Platt Dana, Jankord Ryan, Saar Kathrin, Redei Eva E

Abstract excerpt

Acute stress responsiveness is a quantitative trait that varies in severity from one individual to another; however, the genetic component underlying the individual variation is largely unknown. Fischer 344 (F344) and Wistar Kyoto (WKY) rat strains show large differences in behavioral responsiveness to acute stress, such as freezing behavior in response to footshock during the conditioning phase of contextual...

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PMID: 29529077
DOI: 10.1371/journal.pone.0194293
PMCID: PMC5847310

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