Article
T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.
The Journal of experimental medicine - 1 Dec 1991
Casanova J L, Romero P, Widmann C, Kourilsky P, Maryanski J L
Abstract excerpt
We report here the first extensive study of a T cell repertoire for a class I major histocompatibility complex (MHC)-restricted cytotoxic T lymphocyte (CTL) response. We have found that the T cell receptors (TCRs) carried by 28 H-2Kd-restricted CTL clones specific for a single Plasmodium berghei...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Clone Cells
- Gene Rearrangement, T-Lymphocyte
- H-2 Antigens
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Plasmodium berghei
- Protozoan Proteins
- Receptors, Antigen, T-Cell, alpha-beta