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Article

T cell receptor diversity in CTLs specific for the CTT-1 and CTT-2 minor histocompatibility antigens.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1997

Johnston S L, Wettstein P J

Abstract excerpt

Minor histocompatibility Ags (HA) and their associated immunogenic peptides provide a formidable barrier for successful transplantation, but there is virtually no information regarding the diversity of minor HA-specific TCRs. We have investigated the diversity of alpha- and beta-chains in TCRs specific for the CTT-1 and CTT-2 peptides that are immunodominant in CTL responses to multiple minor HA. CTLs were cloned...

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PMID: 9300679

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