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Article

Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women.

American journal of epidemiology - 15 May 2008

Seitzman Robin L, Mahajan Vinit B, Mangione Carol, Cauley Jane A, Ensrud Kristine E, Stone Katie L, Cummings Steven R, Hochberg Marc C, Hillier Teresa A, Sinsheimer Janet S, Yu Fei, Coleman Anne L

Abstract excerpt

In this study, the authors sought to determine whether single nucleotide polymorphisms in the estrogen receptor alpha (ESR1) and matrix metalloproteinase 2 (MMP2) genes are associated with age-related maculopathy (ARM) in older women. Subjects comprised a random sample of Caucasian women aged > o...

Read the complete abstract on PubMed

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Share to Confounding Factors, Epidemiologic
Share to Estrogen Receptor alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Matrix Metalloproteinase 2

Share to Osteoporosis, Postmenopausal

Share to Pigment Epithelium of Eye

Source

Identifiers

PMID: 18359774
DOI: 10.1093/aje/kwn024

Genes

MMP2
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-18359774-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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