Article
A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy.
Ophthalmic genetics - 1 Dec 2002
Schmidt Silke, Klaver Caroline, Saunders Ann, Postel Eric, De La Paz Monica, Agarwal Anita, Small Kent, Udar Nitin, Ong John, Chalukya Meenal, Nesburn Anthony, Kenney Cristina, Domurath Ruth, Hogan Molly, Mah Tammy, Conley Yvette, Ferrell Robert, Weeks Daniel, de Jong Paulus T V M, van Duijn Cornelia, Haines Jonathan, Pericak-Vance Margaret, Gorin Michael
Abstract excerpt
Age-related maculopathy (ARM) is a multifactorial disorder known to have a substantial genetic component. The epsilon4 allele of the apolipoprotein E gene (APOE-4) has previously been reported to have a protective effect on ARM risk, while the APOE-2 allele may increase disease risk. This study c...
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