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Article

Different activation states of human lymphocytes after antibody-mediated stimulation via CD3 and the alpha/beta T-cell receptor.

Scandinavian journal of immunology - 1 Dec 1990

Schlitt H J, Schwinzer R, Wonigeit K

Abstract excerpt

BMA031 is an IgG2b antibody directed towards the human alpha/beta T-cell receptor that is able to induce proliferation of peripheral blood mononuclear cells independent of antibody crosslinking. The proliferative response to BMA031 during the first 3 days of culture is usually of similar magnitude to that induced by the IgG2a CD3 antibody OKT3 but decreases quickly afterwards. Stimulation by BMA031 induces no...

Topics

Antibodies, Monoclonal
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
Cyclosporins
Cytotoxicity, Immunologic
Humans
Interleukin-2
Kinetics
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muromonab-CD3

Phenotype

Receptors, Antigen, T-Cell

Receptors, Antigen, T-Cell, alpha-beta

Receptors, Interleukin-2

Source

Identifiers

PMID: 2148645
DOI: 10.1111/j.1365-3083.1990.tb03215.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2148645-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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