Article
Upregulation of CXCR1 by proliferating cells in patients with lymphoproliferative disease of granular lymphocytes.
British journal of haematology - 1 Mar 2003
Zambello Renato, Trentin Livio, Facco Monica, Carollo Davide, Cabrelle Anna, Tosoni Alicia, Cannas Giovanna, Nicolardi Linda, Agostini Carlo, Semenzato Gianpietro
Abstract excerpt
The expression and the functional activities of different chemokine receptors (CC motif: CCR1, CCR2, CCR3, CCR5, CCR6; CXC motif: CXCR1, CXCR2, CXCR3, CXCR4, CXCR5) were investigated in 12 patients with lymphoproliferative disease of granular lymphocytes (LDGL). Six patients were characterized by the proliferation of CD3+ve GL and six patients by the expansion of CD3-ve GL. The interleukin 8 (IL-8/CXCL8) receptor...
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