Article
Proliferative responses to PHA, anti-CD3 and antigens in patients with lymphoproliferative disease of granular lymphocytes. Mannoproteins of Candida albicans induce proliferation and cytotoxicity.
Acta haematologica - 1 Jan 1997
Giovannetti A, Quinti I, Rainaldi L, Mauro F R, Oliva A, Pierdominici M, Ricci G, De Rossi G, Cassone A, Aiuti F, Pandolfi F
Abstract excerpt
In this paper we investigated the lymphoproliferative and cytotoxic responses of peripheral blood mononuclear cells (PBMC) of patients affected with lymphoproliferative disease of granular lymphocytes of T cell origin to mitogens and antigens. Most patients with lymphoproliferative disease of granular lymphocytes (LDGL) showed a severely impaired PBMC proliferative capacity in response to phytohemagglutinin,...
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