Article
Polymorphisms in metallothionein-1 and -2 genes associated with the risk of type 2 diabetes mellitus and its complications.
American journal of physiology. Endocrinology and metabolism - 1 May 2008
Yang Lina, Li Hongyan, Yu Ting, Zhao Haijun, Cherian M George, Cai Lu, Liu Ya
Abstract excerpt
Metallothionein (MT) as a potent antioxidant can affect energy metabolism. The present study was undertaken to investigate the association between MT gene polymorphism and type 2 diabetes mellitus. Using the PCR-based restriction fragment length polymorphism method, seven single nucleotide polymorphisms (SNPs) in MT genes (rs8052394 and rs11076161 in MT1A gene, rs8052334, rs964372, and rs7191779 in MT1B gene,...
