Article
Levels of heavy metals and their binding protein metallothionein in type 2 diabetics with kidney disease.
Journal of biochemical and molecular toxicology - 1 Jun 2017
Raudenska Martina, Dvorakova Veronika, Pacal Lukas, Chalasova Katarina, Kratochvilova Monika, Gumulec Jaromir, Ruttkay-Nedecky Branislav, Zitka Ondrej, Kankova Katerina, Adam Vojtech, Masarik Michal
Abstract excerpt
Hyperglycemia, a major metabolic disturbance present in diabetes, promotes oxidative stress. Activation of antioxidant defense is an important mechanism to prevent cell damage. Levels of heavy metals and their binding proteins can contribute to oxidative stress. Antiradical capacity and levels of metallothionein (MT), metals (zinc and copper), and selected antioxidants (bilirubin, cysteine, and glutathione) were...
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