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Article

Optimal screening for promising genes in 2-stage designs.

Biostatistics (Oxford, England) - 1 Oct 2008

Moerkerke B, Goetghebeur E

Abstract excerpt

Detecting genetic markers with biologically relevant effects remains a challenge due to multiple testing. Standard analysis methods focus on evidence against the null and protect primarily the type I error. On the other hand, the worthwhile alternative is specified for power calculations at the design stage. The balanced test as proposed by Moerkerke and others (2006) and Moerkerke and Goetghebeur (2006)...

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Identifiers

PMID: 18349035
DOI: 10.1093/biostatistics/kxn002
PMCID: PMC2536725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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