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Article

Structural and functional analysis of the HSP90AA1 gene: distribution of polymorphisms among sheep with different responses to scrapie.

Cell stress & chaperones - 1 Jan 2008

Marcos-Carcavilla Ane, Calvo Jorge H, González Carmen, Moazami-Goudarzi Katayoun, Laurent Pascal, Bertaud Maud, Hayes Hélène, Beattie Anne E, Serrano Carmen, Lyahyai Jaber, Martín-Burriel Inmaculada, Serrano Magdalena

Abstract excerpt

Scrapie is a transmissible spongiform encephalopathy in sheep and goats. Susceptibility to this neurodegenerative disease is mainly controlled by point mutations at the PRNP locus. Other genes, apart from PRNP, have been reported to modulate resistance/susceptibility to scrapie. On the basis of several studies in Alzheimer and different transmissible spongiform encephalopathy models, HSP90AA1 was chosen as a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18347938
DOI: 10.1007/s12192-007-0004-2
PMCID: PMC2666211

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural and functional analysis of the HSP90AA1 gene: distribution of polymorphisms among sheep with different responses to scrapie.PMID 18347938Read ↗

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Structural and functional analysis of the ovine laminin receptor gene (RPSA): Possible involvement of the LRP/LR protein in scrapie response.Semantic proximity Read ↗

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