Article
Linkage disequilibrium across six prion gene regions spanning 20 kbp in U.S. sheep.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2006
Green Benedict T, Heaton Michael P, Clawson Michael L, Laegreid William W
Abstract excerpt
Single nucleotide polymorphisms (SNPs) and haplotype alleles within the prion gene (PRNP) coding sequence of domestic sheep (Ovis aries) are associated with genetic predisposition to scrapie, a transmissible spongiform encephalopathy disease of sheep. This report describes regions of linkage disequilibrium (LD) throughout the PRNP gene region in U.S. sheep and provides a genetic framework for identifying...
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