Article
A SNP in the HSP90AA1 gene 5' flanking region is associated with the adaptation to differential thermal conditions in the ovine species.
Cell stress & chaperones - 1 Jan 2010
Marcos-Carcavilla Ane, Mutikainen Mari, González Carmen, Calvo Jorge H, Kantanen Juha, Sanz Albina, Marzanov Nurbiy S, Pérez-Guzmán María D, Serrano Magdalena
Abstract excerpt
Molecular chaperones have long been understood to be preferentially transcribed in response to multiple perturbations of the cellular homeostasis. In this study, several polymorphisms in the gene encoding the inducible form of the cytoplasmic Hsp90 (HSP90AA1) were addressed in 24 sheep breeds reared in different climatic regions of Europe, Africa, and Asia. Significant differences in the genotype frequencies for...
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