Article
Identification of new quantitative trait Loci (other than the PRNP gene) modulating the scrapie incubation period in sheep.
Genetics - 1 May 2008
Moreno C R, Cosseddu G M, Schibler L, Roig A, Moazami-Goudarzi K, Andreoletti O, Eychenne F, Lajous D, Schelcher F, Cribiu E P, Laurent P, Vaiman D, Elsen J M
Abstract excerpt
Although susceptibility to scrapie is largely controlled by the PRNP gene, we have searched for additional genomic regions that affect scrapie incubation time in sheep, using two half-sib families with a susceptible PRNP genotype and naturally infected by scrapie. Quantitative trait loci were detected on OAR6 and OAR18.
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