Article
Biodiversity and selection for scrapie resistance in sheep: genetic polymorphism in eight breeds of Algeria.
Journal of genetics - 1 Jun 2018
Djaout Amal, Chiappini Barbara, Gaouar S Bechir Suheil, Afri-Bouzebda Farida, Conte Michela, Chekkal Fakhreddine, El-Bouyahiaoui Rachid, Boukhari Rachid, Agrimi Umberto, Vaccari Gabriele
Abstract excerpt
Scrapie is a prion disease that affects the sheep and goats. It belongs to the group of transmissible spongiform encephalopathies (TSE). TSEs are characterized by the accumulation of the pathological form (PrPSc) of the cellular prion protein (PrPC). The susceptibility of sheep to scrapie is influenced by polymorphisms in the PrP gene (PRNP). The aim of this study was to identify the genetic variability of sheep...
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