Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Agelastatin A: a novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formation

1 Mar 2008

Abstract excerpt

Effective inhibitors of osteopontin (OPN)-mediated neoplastic transformation and metastasis are still lacking. (-)-Agelastatin A is a naturally occurring oroidin alkaloid with powerful antitumor effects that, in many cases, are superior to cisplatin in vitro. In this regard, past comparative assaying of the two agents against a range of human tumor cell lines has revealed that typically (-)-agelastatin A is 1.5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to Cancer Research and Treatments
Share to dental development and anomalies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18347142
DOI: 10.1158/1535-7163.mct-07-2251

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Agelastatin A: a novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formationPMID 18347142Read ↗

Betaine Induces Apoptosis and Inhibits Invasion in OSCC Cell LinesSemantic proximity Read ↗

Osteopontin: role in cell signaling and cancer progressionSemantic proximity Read ↗

Boehmeria Nivea Extract (BNE-RRC) Reverses Epithelial-Mesenchymal Transition and Inhibits Anchorage-Independent Growth in Tumor CellsSemantic proximity Read ↗

Role of osteopontin in the pathophysiology of cancerSemantic proximity Read ↗

Eprinomectin: a derivative of ivermectin suppresses growth and metastatic phenotypes of prostate cancer cells by targeting the β-catenin signaling pathway.Semantic proximity Read ↗

Combined Treatment of Heteronemin and Tetrac Induces Antiproliferation in Oral Cancer CellsSemantic proximity Read ↗

Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: an Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis.Semantic proximity Read ↗

Chalcone Derivatives 4′-Amino-1-Naphthyl-Chalcone (D14) and 4′-Amino-4-Methyl-1-Naphthyl-Chalcone (D15) Suppress Migration and Invasion of Osteosarcoma Cells Mediated by p53 Regulating EMT-Related GenesSemantic proximity Read ↗

Role of osteopontin in cellular signaling and metastatic phenotype.Semantic proximity Read ↗

Role of osteopontin in tumour progressionSemantic proximity Read ↗

Parafibromin inhibits cancer cell growth and causes G1 phase arrest.Semantic proximity Read ↗

Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.