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Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease

1 Feb 2007

Abstract excerpt

Aberrant DNA methylation occurs early in oncogenesis, is stable, and can be assayed in tissues and body fluids. Therefore, genes with aberrant methylation can provide clues for understanding tumor pathways and are attractive candidates for detection of early neoplastic events. Identification of sequences that optimally discriminate cancer from other diseased and healthy tissues is needed to advance both...

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Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
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PMID: 17314273
DOI: 10.1158/1541-7786.mcr-06-0034

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