Immune responses in newly developed short-lived SAM mice. IV. Chromosomal location of a gene controlling defective helper T-cell activity.

Article

Immune responses in newly developed short-lived SAM mice. IV. Chromosomal location of a gene controlling defective helper T-cell activity.

Immunology - 1 Sept 1991

Hanada K, Katoh H, Hosokawa T, Hosono M, Takeda T

Abstract excerpt

Short-lived SAMP-P/1 mice are low responders in in vitro antibody responses because of a selectively impaired helper T(Th)-cell activity. After crossing with high responders (B10.BR mice), about 12% of (B10.BR x SAM-P/1) (BRP)F2 mice showed low responsiveness, as did SAM-P/1 mice, against two T-d...

Topics

Animals
Antibody Formation
B-Lymphocytes
Chromosome Mapping
Erythrocytes
Genetic Linkage
Genetic Markers
Genotype
Lymphocyte Activation
Mice
Mice, Inbred Strains
Spleen
T-Lymphocytes
T-Lymphocytes, Helper-Inducer

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