Article
Effects of beta-adrenoceptor blockade on the phenotypic characteristics of thymocytes and peripheral blood lymphocytes.
The International journal of neuroscience - 1 Dec 2003
Rauski Aleksandra, Kosec Dusko, Vidić-Danković Biljana, Plećas-Solarović Bosiljka, Leposavić Gordana
Abstract excerpt
The study revealed that beta-adrenoceptor blockade with propranolol (0.40 mg/100 g/day, s.c.) in adult male DA rats: (i) increased the thymocyte proliferation and apoptosis, (ii) caused disturbances in kinetics of T cell differentiation leading to distinguishable changes in relative proportion of thymocytes at distinct maturational steps and to an expansion of the most mature single positive (CD4+, CD8+)...
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