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Article

Interleukin 6 gene polymorphisms are not associated with aneurysmal subarachnoid haemorrhage in an Italian population.

Journal of neurology, neurosurgery, and psychiatry - 1 Apr 2008

Fontanella M, Rainero I, Gallone S, Rubino E, Fenoglio P, Valfrè W, Garbossa D, Benevello C, Ducati A, Pinessi L

Abstract excerpt

OBJECTIVE: Several lines of evidence indicate a role for inflammatory processes in the development of cerebral aneurysms. Recently, polymorphisms in the promoter region of the interleukin 6 (IL6) gene were shown to be associated with intracranial aneurysmal disease. The purpose of this study was to verify the association of two functionally active polymorphisms (-174 G>C and -572 G>C) in the promoter region of...

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Identifiers

PMID: 18344399
DOI: 10.1136/jnnp.2007.131565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interleukin 6 gene polymorphisms are not associated with aneurysmal subarachnoid haemorrhage in an Italian population.PMID 18344399Read ↗

Interleukin 6-174G>C polymorphism and risk of aneurysmal subarachnoid hemorrhage: case-control study and meta-analysis.Semantic proximity Read ↗

The interleukin-6 gene -174G>C and -572G>C promoter polymorphisms are related to cerebral aneurysms.Semantic proximity Read ↗

Gene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-6 -174G>C and -572G>C (Part II).Semantic proximity Read ↗

The interleukin-6 gene -572G>C promoter polymorphism is related to intracranial aneurysms in Chinese Han nationality.Semantic proximity Read ↗

The association between interleukin-6 gene polymorphisms and intracranial aneurysms: a meta-analysis.Semantic proximity Read ↗

The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: analysis in two Chinese populations.Semantic proximity Read ↗

Lack of an association between interleukin-6 gene promoter polymorphisms (-174G/C, -572G/C) and ischemic heart disease and/or ischemic stroke: a meta-analysis.Semantic proximity Read ↗

The -174 G/C polymorphism of the interleukin-6 gene promoter and essential hypertension in an elderly Italian population.Semantic proximity Read ↗

Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome.Semantic proximity Read ↗

The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension.Semantic proximity Read ↗

Polymorphisms of Inflammatory Cytokine Genes and Risk for Intracranial Aneurysm: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Association between inflammatory markers and the interleukin-6 -174 G/C polymorphism is abolished in peripheral arterial occlusive disease.Semantic proximity Read ↗

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